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Posted by john on August 26th, 2007 — in Clarinex News
You would think that would mean fewer weeds to cause problems during allergy season. But here’s some discouraging news. This is the time of year Atlanta native Shannon Dollerschell prepares to face the enemy.
Allergy patient Shannon Dollerschell recites her enemies list: “Grass…pollen…mold…mildew…ragweed….everything outside, just about…oak trees…pine trees…”
She assembles a veritable arsenal for her defense.
“Nasal spray, allergy medicine and then I also get shots on a regular basis.”
The fall allergy season has officially begun. Dr. Stan Fineman of the Atlanta Allergy and Asthma Clinic is already seeing the fallout.
“What we’re seeing,” recounted Dr. Fineman, “is patients coming in saying that they have a feeling of weight on their chest. They just can’t get a full breath because of this heat and just oppressive climate outside.”
These weather conditions keep enough crud in the air to make Atlanta’s skyline look like it’s been smeared with chicken fat.
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The heat and the drought have had an obvious impact on Atlanta’s air quality this summer…but you might also think that it might knock down the plants and the weeds that would contribute to fall allergy season.
In fact, the opposite is true.
“It is likely to make it worse,” proclaimed Jessica Groleau of the Atlanta Botanical Garden. “Ragweed’s a very, very tough weed. That’s most of the reason why we call weeds, weeds; is they’re very hard to control and they can live even with this drought.”
When plants die from the drought they leave more space for weeds to grow. Even if ragweed is stressed, its defense is to put out pollen.
“The ragweed season is starting up now,” said Fineman. “We’re already starting to count ragweed pollen on our counting station…so we know it’s in the air…and we anticipate that we’re gonna see more ragweed pollen in the next few weeks.”
Most ragweed won’t be in bloom for another two or three weeks and will hang around until the first frost.
There is a harmonic convergence of conditions to make this allergy season just horrible. At least, Shannon Dollerschell knows to get ready for it.
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Posted by john on August 19th, 2007 — in Clarinex News
Tom Norrington Davies, Allegra McEvedy and Mark Bittman
Sunday August 19, 2007
Observer Food Monthly
We often can’t be bothered to think about cooking during the summer holidays. But with a little imagination even the laziest cook can rustle up something a lot more tempting than a standard ham salad. We asked two of our favourite chefs, Tom Norrington-Davies and Allegra McEvedy, and top New York food writer, Mark Bittman, to come up with a list of quick and easy alternatives.
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The result was 101 dishes, all of which get you in and out of the kitchen in 10 minutes or less (we’re not counting the time it takes to bring water to the boil). These suggestions are not formal recipes; rather, they provide a general outline so that with a few simple ingredients you can turn any idea on this list into a meal for two.
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Posted by john on August 15th, 2007 — in Clarinex News
While many people are aware of how dangerous software patents are to innovation in the software space, not nearly as many feel the same way about pharmaceutical patents. However, there is increasing evidence that pharmaceutical patents are harming healthcare in a variety of ways, often by slowing the pace of innovation by locking up important concepts and making them too expensive. Recently, India was pressured to update its patent system to cover pharmaceuticals (in many countries, pharma patents are a relatively recent addition), though the rules state that drugs created before 1995 cannot receive patent protection. However, drug makers have long learned that a great way to artificially extend patent protection on a drug is to make a tiny modification and then get a new patent. That’s why you now see Clarinex on the market from the maker of Claritin. Claritin went off patent, so the maker came out with Clarinex, advertising that it was much better, even though that doesn’t actually seem to be the case.
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It seems that pharma firm Novartis tried to use this little trick to sneak in patent protection in India for a leukemia drug that came out before 1995. It tried to get a patent on a slightly modified version of the drug, which would then let it ban the sale of generic versions of the non-patented version of the drug. Luckily, as pointed out at Against Monopoly, an Indian court has denied the request, since Indian law says patents should only be granted for new products, or ones where there’s a significant improvement — which is not at all true in this case. That means generic makers can continue to market their drug in India and many, many more leukemia patients will be able to afford the medicine. Novartis, of course, whines that this will slow down drug development, but the evidence suggests exactly the opposite. Having a truly competitive market increases the incentive for real innovation. What Novartis wants is to focus on marginal, useless innovation for the sake of keeping monopoly profits.
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Posted by john on August 10th, 2007 — in Clarinex News
Asthmatic adults living in inner-city areas are often allergic to many triggers, such as dust mites or pets, but this sensitization does not appear to increase the severity of their asthma.
“We were expecting that sensitization would be related to worse asthma outcomes, as in children,” lead investigator Dr. Juan P. Wisnivesky told Reuters Health.
“Inner-city adults are heavily exposed to these allergens and are commonly sensitized — as shown in our study, as well as by others,” he noted. “Thus, we were expecting to find an association between sensitization and asthma contro
Wisnivesky, from the Mount Sinai School of Medicine, New York, and his associates evaluated 245 inner-city adults with persistent asthma. The patients were mostly women, insured by Medicaid. Sixty percent were Hispanic, 30% African American, and 5% were white. The average income for most patients was less than $15,000 per year.
After being tested for sensitization to cockroaches, dust mites, cat, mold and mouse, 152 (62 percent) of the patients were found to be positive for at least one of these indoor allergens.
However, scores on a standardized questionnaire assessing asthma control were not significantly worse among patients sensitized to indoor allergens compared with those who were not, the team reports in the Journal of Allergy and Clinical Immunology.
“This is not to say that there is not an important allergic component to asthma,” Wisnivesky commented. “The point is that these factors may be more relevant in children than in adults.”
Given these results, Wisnivesky says doctors with adult asthma patients should “focus less on assessing sensitization or educating the patients on environmental factors, and pay attention to other issues, such as how patients use their inhaled corticosteroids or if they understand that asthma is a chronic disease.”
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Posted by john on August 6th, 2007 — in Clarinex News
European cruise operator Costa Cruises has extended its Far East programme to introduce Japan with 14 and 15-night sailings for 2008. The operator will offer two sailings on board Costa Allegra – 21 June 2008 for 15 nights or 12 October 2008 for 14 nights.
The 15-night June itinerary starts from Hong Kong and then calls at Keelung, Naha Okinawa, Kobe, Tokyo, Nagasaki and Cheju before ending in Tianjin
The 14-night journey, departing in October, begins in Shanghai and then sails to Cheju, Nagasaki, Tokyo, Kobe, Naha Okinawa, Keelung and finally, Hong Kong.
Costa Cruises was the first international cruise company authorised to operate in the Chinese market and repositioned its Costa Allegra in Hong Kong last year. The operator firmly believes with the increased interest in the Far East in general and the increased volume of UK visitors to the region the addition of Japan will be a big hit.
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Posted by john on July 29th, 2007 — in Clarinex News
Merck and Schering-Plough each reported strong second-quarter sales results today.
Merck’s second-quarter highlights included:
*Growth in global sales for asthma and allergic rhinitis treatment Singulair by 15% to $1.1 billion.
*Global sales growth of antihypertensive medicines Cozaar and Hyzaar of 8% to $847 million.
*Global sales of $358 million for cervical cancer vaccine Gardasil.
*Global sales of $144 million for Januvia, Merck’s first-in-class treatment for Type 2 diabetes.
Meanwhile, Schering-Plough’s second-quarter sales increased by 13%, to almost $3.2 billion, as the company continues to benefit from a leadership turnaround under Fred Hassan.
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Schering-Plough’s second-quarter highlights included:
*A global sales increase for arthritis drug Remicade of 28% to $394 million.
*A global sales increase for allergy treatment Nasonex of 22% to $295 million.
*A global sales increase for seasonal allergic rhinitis drug Clarinex to $250 million from $226 million.
*International sales growth for Temodar, a treatment for certain types of brain tumors of 26% to $216 million.
*An increase in sales of Pegintron for hepatitis C of 3% to $234 million, due to higher sales in Latin America and Europe, and tempered by lower sales in the United States and Japan.
Merck and Schering-Plough’s quarterly performance was helped by the joint venture between the companies to market cholesterol drugs Vytorin and Zetia. Sales of the drugs rose $1.3 billion in the quarter, up 30% from a year earlier.
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Posted by john on July 25th, 2007 — in Clarinex News
She will also kick up her heels on the new series of Dancing With The Stars.
“I’m going to have a ball swapping my sneakers for dancing shoes,” Rowe said in a statement.
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“This is an opportunity which gives me the chance to balance my number one priority - being a mum to Allegra - with returning to work.”
Rowe recently parted ways with the Nine network, where she had presented the Today show before taking maternity leave last December.
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Posted by john on July 22nd, 2007 — in Clarinex News
Eton Systems, the world’s leading provider of unit production systems (UPS) for the sewn-product industries, announces that National Allergy Supply Inc, the nation’s largest allergy, asthma, and sinus products supplier, will implement the Eton materials handling and factory floor data collection system in its Cornelia, Georgia (USA) manufacturing facility.
The planned August installation will automate the entire sewing operation of the company’s production of mattress and pillow encasings, which provide protection against dust mite allergen for allergic and asthmatic patients.
Headquartered in Duluth, Georgia, National Allergy Supply markets a wide range of healthy bedding, allergen control, air filtration, asthma treatment, and other personal care products directly to patients based on physician referrals and through specialty retailers.
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In business for 17 years, the marketing company joined together with its manufacturing business in 2004 to form an employee stock ownership plan (ESOP) that made the company’s 60+ employees owners in the company. The company is the largest physician referred supplier in this fast-growing market.
In response to this business growth, National Allergy Supply is automating its entire manufacturing operation, focusing primarily on a new automated cutting system and the Eton production system.
“Domestic manufacturing is essential to producing the quality that differentiates our product”, noted Lee Hardy, general manager and vice president of manufacturing. “It’s not just the fabric you use, it’s the way you construct these products that makes them functional.”
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Posted by john on July 17th, 2007 — in Clarinex News
More and more foods bear a mishmash of warnings that they might accidentally contain ingredients that could seriously sicken people with food allergies. Yet there are signs that the labels are creating confusion among families that should heed them _ even as new testing shows there is a real, if probably small, chance that foods with even the most vaguely worded warnings truly pose a risk.
The disconnect is sparking calls for standards on what are now voluntary warning labels. The Food and Drug Administration plans to seek advice from consumers and food makers, perhaps by year’s end, before considering whether to intervene.
Penny and Dean Ackerman pose with their children Emily, 6, and Gregory, 3, in their home in Bethlehem, Pa., Sunday July 15, 2007 More and more foods bear warnings that they might accidentally contain peanuts or other ingredients that can sicken some of the 12 million Americans with food allergies. But there are growing signs that the labels are creating confusion among families who should be heeding them, sparking calls for standards on this voluntary warning system. (AP Photo/Rick Smith)
Penny and Dean Ackerman pose with their children Emily, 6, and Gregory, 3, in their home in Bethlehem, Pa., Sunday July 15, 2007 More and more foods bear warnings that they might accidentally contain peanuts or other ingredients that can sicken some of the 12 million Americans with food allergies. But there are growing signs that the labels are creating confusion among families who should be heeding them, sparking calls for standards on this voluntary warning system. (AP Photo/Rick Smith) (Rick Smith - AP)
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Worried the labels may be losing credibility, the industry’s Grocery Manufacturers/Food Products Association already is preparing to update its own guidelines on when foods should carry the warnings.
Consumers see the label “on so many products, they say, ‘Oh heck, I’m going to ignore it,’” laments Dr. Steve Taylor, a food scientist at the University of Nebraska who co-authored a recent study about the confusion.
For the seriously allergic, “I’ve characterized it as akin to playing Russian roulette with a really big gun that has 100 chambers and only one bullet. Sooner or later if you eat these products, you’re going to eat the wrong one,” he said.
About 12 million Americans have some degree of food allergy. Severe food allergies trigger 30,000 emergency room visits a year, and 150 to 200 deaths a year. Food labels help the allergic avoid ingredients that could sicken them.
A law that took effect last year requires foods that intentionally contain highly allergenic ingredients such as peanuts, shellfish or eggs to disclose that in plain language.
The accidental-allergy warnings are different: They’re aimed at foods that aren’t supposed to contain a particular allergen but might become contaminated with it. They may be made in the same factory, or on the same machines as allergen-containing goods.
In a report to Congress last year, FDA said a quarter of recently inspected food factories had the potential for such a mix-up.
The warnings are voluntary, so different companies use different, sometimes vague, wording. Nor does anyone count how many foods bear them, although all sides agree more are. Enter the new research, in this month’s Journal of Allergy and Clinical Immunology.
First, the Food Allergy & Anaphylaxis Network, an influential consumer group, surveyed more than 600 parents of food-allergic children. In 2006, 75 percent said they would never buy a food with an accidental-allergy warning _ down from 85 percent when the network posed the same question in 2003.
A warning’s wording determined if some parents ignored it: “May contain peanuts” sounds scarier than “packaged in a facility that processes peanuts” _ and thus 88 percent said they heeded the first warning while just 64 percent heeded the latter.
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Posted by john on July 15th, 2007 — in Clarinex News
The Rock Cats’ stadium crew sprayed a garden hose into the stands Monday to comfort perspiring fans, but the cold shower did not affect Reading batters.
The Phillies beat the Rock Cats 8-5 to spoil New Britain’s bid for five consecutive wins entering the Eastern League All-Star break.
“On a hot day like today when we drew first blood, giving up eight runs in the middle innings is tough to overcome,” manager Riccardo Ingram said.
Jesse Floyd (4-7, 4.67 ERA) gave up five runs in the fourth as the thermometer in center field reached 99 degrees. Second baseman Peeter Ramos chased Floyd with a three-run homer to left.
Reading scored three more runs in the fifth before a paid crowd of 4,811 at New Britain Stadium, though many stayed home because of the heat. Ingram said the Rock Cats were disappointed about missing a chance to get back to .500 after struggling in June.
“Heading into two days off at .500 would have been great,” he said. “But we fell short.”
New Britain scored two runs in the seventh and one in the eighth. But Matt Allegra, who hit home runs in the fourth and eighth innings, lined out with two out and the bases loaded in the ninth.
“Guys fought hard. We had a chance right until the final out,” Ingram said.
Matt Moses’ RBI double in the third put New Britain up 1-0, and the Rock Cats scored a run in the fourth on Allegra’s first home run.
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Reading shortstop Michael Garciaparra, the younger brother of former Red Sox All-Star Nomar Garciaparra, went 0-for-4 and is hitting .257.
Seattle drafted Garciaparra 36th overall in 2001 with the pick awarded for the free agent departure of Alex Rodriguez. But Garciaparra has struggled to live up to his billing as a future major leaguer.
After the All-Star Game Wednesday at Dodd Stadium in Norwich, the Rock Cats travel to Portland, Maine, for four games before an eight-game homestand against the Defenders and Thunder.
“This second half is going to be crucial for us,” Ingram said. “The first couple series will probably dictate the outcome of our season, so we have to come out ready to play.”
Defenders 6, Mets 4: Simon Klink hit a three-run homer in the seventh for a 4-3 lead and hit a sacrifice fly to score Alex Requena in a two-run ninth as Connecticut beat the Mets in Binghamton, N.Y. Brian Anderson gave up a homer to the Mets’ Mark Kiger with one out in the ninth before completing his 20th save.
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